Lille beat Genoa to a place in the knock-out phase of the Europa League with a clinical performance to defeat Slavia Prague 3-1 in their Group B encounter at the Metropole.
Yohan Cabaye opened the scoring after 25 minutes before Gervinho netted six minutes before half-time to put Lille firmly in control.
Stanislav Vicek gave Slavia hope when he found the target after 56 minutes but Ludovic Obraniak eased any lingering nerves when he converted 10 minutes from time.
The French Ligue 1 side needed to match or better Genoa's result against table-toppers Valencia, where the Serie A team eventually going down 2-1 to a last-minute winner.
Bruno put the Spanish side ahead on the stroke of half-time to give the Italians a mountain to climb, but Hernan Crespo equalised in the 51st minute to give them hope.
David Villa then grabbed the winner for Valencia in the final minute.
in Group A, Anderlecht qualified with a convincing 3-1 victory at Ajax to pip the Amsterdammers to top spot.
Heading to Holland in second place in the pool, two points clear of Dinamo Zagreb, Herman van Holsbeeck's side knew a draw would be good enough to see them advance.
But the Belgian outfit went one better thanks to goals from Romelu Lukaku (two) and Jonathan Legear. Urby Emanuelson grabbed a late consolation for the hosts.
Timisoara defeated Dinamo 2-1 in the group's other match.
The Croatians fell behind when Gheorghe Bucur opened the scoring for the hosts midway through the second period but parity was restored when Cristian Scutaru put through his own net in the final 10 minutes. Dorin Goga hit the winner six minutes before time to hand the Romanians a first win.
Hapoel Tel Aviv beat Hamburg 1-0 to capture top spot in Group C and send the Germans into second place.
Both teams had already qualified but Samuel Yeboah's goal was enough to see the Israeli side through in first place.
FC Twente advanced despite being held to a draw at Steaua Bucharest in Group H, after table-toppers Fenerbahce beat FC Sheriff 1-0.
That meant Twente did not require victory to go through in second place.
The Eredivisie outfit secured a point when Ronnie Stam's deflected equaliser cancelled out Pantelis Kapetanos' opener.
Fenerbahce's win came courtesy of a 15th-minute strike from Ugur Boral.
In Group G, Salzburg maintained their 100% record with a 1-0 win over second-placed Villarreal thanks to Dusan Svento's goal.
Bottom-placed Levski SofiaM closed their campaign on a high after Hristo Yovov scored the only goal of their game with Lazio.
Angel Di Maria bagged a brace as Benfica rubber-stamped their status as winners of Group I with a battling 2-1 win at against AEK Athens.
Di Maria made sure of the points with long-range efforts in either half while Ismael Blanco bagged a late consolation for AEK.
